Reusing provenance information captured in WebProv for automatic generation of experiment specifications

Budde, Kai and Wilsdorf, Pia and Smith, Jacob and Haack, Fiete and Ruscheinski, Andreas and Uhrmacher, Adelinde M. (2019) Reusing provenance information captured in WebProv for automatic generation of experiment specifications. In: INCOME 2019 (Integrative pathway modeling in systems biology and systems medicine), 25-29 Nov 2019, Berlin, Germany.

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Abstract

The provenance of a simulation model provides important context about its generation in a structured and computer-accessible form which facilitates interpreting and thus reusing the simulation model. It includes information about (i) simulation experiments that have been executed, (ii) data that has been used as input for calibration or validation of the simulation model, or (iii) other simulation models it has been based upon or cross-validated with [1]. In [2] we have presented the web-based provenance tool WebProv to access, store, and display the provenance information of simulation studies using the PROV ontology. In combination with WebProv, we will show how our template-based simulation experiment generation approach [3] can facilitate the automatic generation and execution of simulation experiments across simulation studies, thus supporting the development of valid simulation models. As an example, we have captured provenance information of different models of canonical Wnt signaling and discuss which information is needed for automatically generating various types of experiments such as sensitivity analyses or cross-validation experiments.

Item Type: Conference or Workshop Item (Speech)
Projects: LaCE, GrEASE