Rule-based multi-level modeling of cell biological systems

Maus, Carsten and Rybacki, Stefan and Uhrmacher, Adelinde M. (2011) Rule-based multi-level modeling of cell biological systems. BMC Systems Biology, 5 (166), ISSN 1752-0509 (electronic version).

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Proteins, individual cells, and cell populations denote different levels of an organizational hierarchy, each of which with its own dynamics. Multi-level modeling is concerned with describing a system at these different levels and relating their dynamics. Rule-based modeling has increasingly attracted attention due to enabling a concise and compact description of biochemical systems. In addition, it allows different methods for model analysis, since more than one semantics can be defined for the same syntax.

Item Type: Article
Projects: DiErMoSiS, CoSa, GRK dIEM oSiRiS