Bittig, Arne T. and Uhrmacher, Adelinde M. and Matschegewski, Claudia and Nebe, J. Barbara (2012) Spatial simulation of actin filament dynamics on structured surfaces. In: Winter Simulation Conference (WSC 2012), 09-12 Dec 2012, Berlin, Germany. Proceedings, published by IEEE, 364:1-364:2. Poster.
Full text not available from this repository.Abstract
We develop a simple model of actin filament growth in bone cells comprising integrin receptors, actin molecules able to form chains and cofilin molecules destroying chains. The model is expressed in the ML-Space modeling language and simulated using a particle-based approach. We find the model to be a promising starting point in reproducing in silico experimentally observed filament growth behavior of bone cells on different surface structures.
| Item Type: | Conference or Workshop Item (Poster) |
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